Four other board members agree causing Vogler to leave as chairman and revoke his $100 million donation. The team celebrates Vogler's departure with champagne as Cuddy reminds House this conflict was unnecessary but caused by his temperament. The parents are arrested and charged with child endangerment under the assumption it was caused by their and the baby's vegan diet. The charges are revoked after a CT scan reveals the baby has DiGeorge syndrome, causing the malnourishment. A college student named Brandon (Kevin Zegers) collapses after having sex with his fiancée.
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House's attempt to prove that he doesn't really have ALS causes John Henry to suffer respiratory failure. House intubates him in violation of his DNR and tries to keep him on life support using a legal technicality. Cameron notices a blood clot, which is removed, and MRI reveals an Arteriovenous malformation which is operated on restoring his ability to walk. Meanwhile, Foreman receives a lucrative job offer from John Henry's doctor, his former mentor. After returning from jogging with his best friend, Ed (Dominic Purcell) is uncharacteristically abused by his bedridden wife, Elise (Myndy Crist). House concludes that she either has rabbit fever from cooking rabbits or African sleeping sickness, which must have been sexually transmitted since neither of them has been to Africa.
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After overhearing a conversation about a sick baby, House investigates the maternity ward and predicts an epidemic. After realizing the severity of the disease, Cuddy quarantines the maternity ward. In an effort to discover the source of the epidemic, House begins treating the children. However, when the kidneys of two of the children shut down, House is forced to test which drug caused the failure, resulting in one of the babies dying. Following an autopsy, the team discovers the presence of echovirus 11, CMV, and parvovirus B19 antibodies.
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With support from Stacy, but not from his team, House gives Mark a dangerous drug cocktail to confirm that he really has AIP. House receives a visit from an ex-girlfriend, Stacy Warner, who seeks his help for her husband, Mark. In the meantime, Cuddy forces House to give a lecture to medical students on diagnosing patients and presents three scenarios, each with different reasons for their leg pain (with guest star Carmen Electra). Dr. Foreman believes an uncooperative homeless woman (Leslie Hope) is faking seizures to get a meal ticket at the hospital.
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They both strongly deny having an affair so House starts treatment for rabbit fever. She confesses to an affair with her husband's best friend, causing her husband to leave her. He has recently hired Eric Foreman, who, despite his considerable academic background, appears to have been hired because he was a juvenile delinquent. House plans on using him to break into patients' homes to look for diagnostic clues. The series House (also known as House, M.D.) began its first season on November 16, 2004 in the United States and was picked up for a full run of 22 episodes. Season 1 gained high Nielsen ratings, averaging 13.3 million viewers an episode.
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House insults Vogler and his company during the speech, reigniting their feud. After consulting a Ouija board, a young boy (Daryl Sabara) believes he is going to die, and is sent to Princeton-Plainsboro after suffering from pneumonia. Meanwhile, Chase's estranged father (Patrick Bauchau) comes to the hospital and helps House and his team diagnose the kid.
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House's team discover unused Ampicillin and frozen microwave burgers, supporting House's diagnosis. The tumor is too large to resect but House orders the team to shrink the tumor with an injection of ethanol so that the surgeon will operate. However, Lucille, in a decision House claims to be inconsistent with her schizophrenia, calls Social Services to take her son. The team consider that Wilson's disease could explain all symptoms and an eye exam shows copper-colored rings around her irises.
Dr. Gregory House is devoid of bedside manner and wouldn't even talk to his patients if he could get away with it. Dealing with his own constant physical pain, he uses a cane that seems to punctuate his acerbic, brutally honest demeanor. While his behavior can border on antisocial, House is a maverick physician whose unconventional thinking and flawless instincts have afforded him a great deal of respect.
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They test the mothers and decide the cause of the epidemic is the Echovirus. Using an experimental antivirus, they successfully cure the remaining babies. House, determined to find the entry point of the virus, finds an elderly hospital volunteer coughing and wiping her nose as she pushes around a cart of baby toys and blankets and makes the connection. House and his team investigate an overweight ten-year-old girl (Jennifer Stone) who has a heart attack and her mother (Cynthia Ettinger) insists that House and his team look past her weight to find the diagnosis. Adding to his stress, Vogler demands House get rid of a member of his team. It is revealed that Chase has been feeding Vogler information about House's cases.
Region 2 DVDs were released on February 27, 2006, and Region 4 DVDs were released on November 28, 2006. Season One was re-released in the anamorphic widescreen format on February 10, 2009. Eventually it is discovered that both youths bought very cheap pairs of jeans at a car boot sale. Meanwhile, House has an old lady hit on him who turns out to have Neurosyphilis.
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House suspects Hank – with a history of drug abuse – is lying about using steroids, as his condition worsens. When Hank's kidneys start to fail, his wife (Meredith Monroe) offers to donate hers, but she will have to abort her early pregnancy, something Hank does not want. Eventually House finds out the wife suffers from loss of smell, indicating the pair have smoked cannabis which was grown on cadmium polluted soil. Meanwhile, Foreman dates a pharmaceutical representative and House goes to a monster truck rally with Cameron.This episode features a cameo appearance by the series' director and executive producer Bryan Singer. John Henry Giles (Harry Lennix), a legendary jazz musician with ALS, is brought in to be treated by Foreman for pneumonia.
Dan suffers from an auditory hallucination during a procedure, however, ruling out House's diagnosis. Using coffee cups from the parents, House does an unauthorized paternity test and discovers that neither parent is biologically related to Dan. House flashbacks to a case he had earlier that involved a mother who did not want her baby to be vaccinated and theorizes that Dan is suffering from a measles virus contracted during his childhood. House confirms his diagnosis with a retinal biopsy and successfully cures Dan.
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